Linked Life Data

7844642

Source:http://linkedlifedata.com/resource/pubmed/id/7844642

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-3-8
pubmed:abstractText
The differential effects of dietary proteins on the metabolic process of eicosapentaenoic acid (EPA, 20:5n-3) via docosapentaenoic acid (DPA, 22:5n-3) to docosahexaenoic acid (DHA, 22:6n-3) were studied using parameters calculated from the proportion of n-3 polyenoic acid in liver phospholipid (PL) of rats. Rats were given casein or soy-protein isolate (SPI) diet containing 3% EPA with or without methionine (Met) supplementation for 3 weeks. The (22:5 + 22:6)/20:5 and 22:5/20:5 ratios of the PL fractions in the liver of rats given SPI were evidently elevated compared with those given casein. These ratios were also elevated when linoleic acid (LA, 18:2n-6) was added to the diet. There were no significant differences in the 22:6/22:5 ratio of the same PL fractions between the casein and SPI groups without the addition of LA, but the ratio was lowered by the addition of LA. It was found that these parameters for metabolic conversion were not affected by supplementation of Met or by a decrease in body weight. The above results suggest that the elongation step from EPA to DPA is affected by the type of protein, i.e., it is accelerated by SPI and is not affected by the presence of LA, while the metabolic process from DPA to DHA is not affected by the type of proteins without the addition of LA but is suppressed when LA is added.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0301-4800
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-62
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Effects of dietary casein and soy-protein on metabolic conversion of eicosapentaenoic acid to docosahexaenoic acid in the liver of rat.
pubmed:affiliation
Department of Nutrition, Faculty of Agriculture, Tokyo University of Agriculture, Japan.
pubmed:publicationType
Journal Article