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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-3-9
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pubmed:abstractText |
We studied a patient who developed pure red cell aplasia (PRCA) following peripheral stem cell transplantation for non-Hodgkin lymphoma. Serum erythropoietin was appropriate for the degree of anemia. Corticosteroid treatment was ineffective. Four months after transplantation rHuEpo was administered subcutaneously at a dose of 150 U/Kg per day, five days a week for 8 weeks. Treatment induced an erythropoietic response and corrected anemia. Response was maintained following discontinuation of rHuEpo. This study and previous reports indicate that high doses of rHuEpo given over a short time can resolve PRCA following autologous or allogeneic stem cell transplantation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0390-6078
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
456-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7843633-Dose-Response Relationship, Drug,
pubmed-meshheading:7843633-Erythropoietin,
pubmed-meshheading:7843633-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:7843633-Humans,
pubmed-meshheading:7843633-Male,
pubmed-meshheading:7843633-Middle Aged,
pubmed-meshheading:7843633-Recombinant Proteins,
pubmed-meshheading:7843633-Red-Cell Aplasia, Pure,
pubmed-meshheading:7843633-Time Factors
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pubmed:articleTitle |
Pure red cell aplasia following peripheral stem cell transplantation: complete response to a short course of high-dose recombinant human erythropoietin.
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pubmed:affiliation |
Department of Human Biopathology, University La Sapienza, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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