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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-2-27
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pubmed:abstractText |
In Nigeria, severe NNJ is common in babies exposed to mothballs and other icterogenic agents. High-performance liquid chromatographic (HPLC) method was employed for quantitative analysis of 1 and 2-naphtol in the urine of 50 neonates aged one to 19 days. Five of the 25 babies who had a history of exposure to mothballs, and none of the babies without a history of exposure had 1-naphtol in their urine. The value of 1-naphtol ranged between 0.75 and 11.69 micrograms/ml with mean of 5 +/- 5 micrograms/ml. The overall correlation coefficient (r) between bilirubin values and 1-naphtol was 0.1 while it was 1 in the three G-6-PD deficient infants. The procedure will be very useful in the evaluation of infants with unexplained NNJ, anaemia, acute haemolytic jaundice and haemoglobinuria if naphthalene poisoning is suspected.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0309-3913
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7839885-Anemia,
pubmed-meshheading:7839885-Bilirubin,
pubmed-meshheading:7839885-Chromatography, High Pressure Liquid,
pubmed-meshheading:7839885-Environmental Exposure,
pubmed-meshheading:7839885-Female,
pubmed-meshheading:7839885-Humans,
pubmed-meshheading:7839885-Infant, Newborn,
pubmed-meshheading:7839885-Jaundice, Neonatal,
pubmed-meshheading:7839885-Male,
pubmed-meshheading:7839885-Naphthalenes,
pubmed-meshheading:7839885-Naphthols,
pubmed-meshheading:7839885-Reproducibility of Results,
pubmed-meshheading:7839885-Sensitivity and Specificity
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pubmed:year |
1993
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pubmed:articleTitle |
Quantitative analysis of 1-naphthol in urine of neonates exposed to mothballs: the value in infants with unexplained anaemia.
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pubmed:affiliation |
Department of Paediatrics, Obafemi Awolowo University, Ile-Ife.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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