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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1995-2-28
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pubmed:abstractText |
From January 1993 to January 1994, scintigraphy with 123I-MIBG and/or 131I-MIBG were performed in 22 patients and their scintigraphic usefulness was evaluated. Iodine-123 MIBG and 131I-MIBG scintigrams were obtained 24 hours after injection of 222 MBq of 123I-MIBG and 48 hours after injection of 20 MBq of 131I-MIBG, respectively. In two patients with pheochromocytoma, the 123I-MIBG and 131I-MIBG scans were performed and both images were compared. In a patient with single intraadrenal pheochromocytoma, the lesion not detected with 131I-MIBG was clearly visualized with 123I-MIBG. In the other patient with multiple metastatic pheochromocytoma, much more lesions were distinctly demonstrated on the 123I-MIBG images than on the 131I-MIBG images. All of the lesions were detected with 123I-MIBG in a patient with pheochromocytoma, 3 patients with neuroblastoma and a patient with medullary thyroid cancer. Most of the normal adrenal glands (86%) were visualized on the 123I-MIBG scintigrams, in 7 patients without neural crest tumor and adrenal diseases, while 131I-MIBG scintigraphy failed to visualize normal adrenal glands in 2 hypertensive patients. The main reason for the superiority of 123I-MIBG to 131I-MIBG is considered to be as follows: 1) higher specific activity of 123I-MIBG. 2) the larger amount of 123I-MIBG used. 3) gamma ray energy of 123I is ideal for gamma camera. In conclusion, 123I-MIBG appears to be a more suitable imaging agent than 131I-MIBG in depicting neural crest tumors.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-7854
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1357-64
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pubmed:dateRevised |
2010-4-12
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pubmed:meshHeading |
pubmed-meshheading:7837704-3-Iodobenzylguanidine,
pubmed-meshheading:7837704-Adrenal Gland Neoplasms,
pubmed-meshheading:7837704-Carcinoma, Medullary,
pubmed-meshheading:7837704-Humans,
pubmed-meshheading:7837704-Iodine Radioisotopes,
pubmed-meshheading:7837704-Iodobenzenes,
pubmed-meshheading:7837704-Neuroblastoma,
pubmed-meshheading:7837704-Pheochromocytoma,
pubmed-meshheading:7837704-Thyroid Neoplasms
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pubmed:year |
1994
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pubmed:articleTitle |
[Detection of neural crest tumors by 123I-MIBG scintigraphy].
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pubmed:affiliation |
Department of Nuclear Medicine, Kobe City General Hospital.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract
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