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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-2-27
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pubmed:abstractText |
Cytogenetics, Southern blotting and PCR were used to detect t(14;18) in 72 British patients with follicular lymphoma. The overall incidence of the translocation was 76%. Cytogenetics was the most successful technique, but 10-30% of translocations detected karyotypically were missed by molecular methods, presumably due to break-points falling outside the range of probes and primers used here. Reliance on molecular detection alone may considerably underestimate the incidence of t(14;18) and it is therefore essential to use the most comprehensive range of probes and primers available.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7833271-Base Sequence,
pubmed-meshheading:7833271-Blotting, Southern,
pubmed-meshheading:7833271-Chromosomes, Human, Pair 14,
pubmed-meshheading:7833271-Chromosomes, Human, Pair 18,
pubmed-meshheading:7833271-Humans,
pubmed-meshheading:7833271-Karyotyping,
pubmed-meshheading:7833271-Lymphoma, Follicular,
pubmed-meshheading:7833271-Molecular Sequence Data,
pubmed-meshheading:7833271-Polymerase Chain Reaction,
pubmed-meshheading:7833271-Translocation, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
Detection of t(14;18) in British follicular lymphoma using cytogenetics, Southern blotting and the polymerase chain reaction.
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pubmed:affiliation |
MRC Human Genetics Unit, Edinburgh, Scotland.
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pubmed:publicationType |
Journal Article
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