|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
1995-2-23
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
Human lysosomal alpha-mannosidase has been purified by a simple and rapid method in sufficient quantities for the analysis of its subunit composition and partial protein sequencing. Analysis of the N-terminal residues of the 30 kDa polypeptide has enabled us to confirm the identity of the recently cloned cDNA that was tentatively identified as that of lysosomal alpha-mannosidase [Nebes and Schmidt (1994) Biochem. Biophys. Res. Commun. 200, 239-245] and to locate the position of this polypeptide within the total deduced amino acid sequence. This finding will therefore provide a firm foundation for the characterization of alpha-mannosidosis mutations.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-2148259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-271272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-2965147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-3611052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-3954735,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-4640377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-6626219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-7117229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-8166692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-821469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-8430698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7832746-942051
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0264-6021
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
305 ( Pt 2)
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
363-6
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:7832746-Amino Acid Sequence,
pubmed-meshheading:7832746-DNA, Complementary,
pubmed-meshheading:7832746-Enzyme Stability,
pubmed-meshheading:7832746-Humans,
pubmed-meshheading:7832746-Leukemia,
pubmed-meshheading:7832746-Lysosomes,
pubmed-meshheading:7832746-Mannosidases,
pubmed-meshheading:7832746-Molecular Sequence Data,
pubmed-meshheading:7832746-Sequence Analysis,
pubmed-meshheading:7832746-Sulfates,
pubmed-meshheading:7832746-Tumor Cells, Cultured,
pubmed-meshheading:7832746-Zinc Compounds,
pubmed-meshheading:7832746-Zinc Sulfate,
pubmed-meshheading:7832746-alpha-Mannosidase
|
|
pubmed:year |
1995
|
|
pubmed:articleTitle |
Partial sequence of the purified protein confirms the identity of cDNA coding for human lysosomal alpha-mannosidase B.
|
|
pubmed:affiliation |
Dipartimento di Biologia Cellulare e Molecolare, Università degli Studi di Perugia, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
