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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1995-2-22
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pubmed:abstractText |
A functional factor X deficiency is described which caused pronounced reduction in the in vitro activation of the extrinsic system while marginally affecting the in vitro activation of the intrinsic pathway. All studies were normal with the exception of a prolonged PT, an elevated factor X antigen, and low factor X activity. Western blot analysis revealed the presence of two factor X species. The abnormal molecule was of higher molecular weight. Interestingly, there was no bleeding associated with this deficiency. The biochemical basis of this defect is currently under investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-4
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:7832186-Adult,
pubmed-meshheading:7832186-Blotting, Western,
pubmed-meshheading:7832186-Factor X,
pubmed-meshheading:7832186-Factor X Deficiency,
pubmed-meshheading:7832186-Female,
pubmed-meshheading:7832186-Hematologic Tests,
pubmed-meshheading:7832186-Humans,
pubmed-meshheading:7832186-Molecular Weight
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pubmed:year |
1995
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pubmed:articleTitle |
A functional factor X deficiency.
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pubmed:affiliation |
Department of Medicine, University of Missouri, Columbia 65212.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|