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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1995-2-23
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pubmed:abstractText |
The risk of neuroleptic-induced tardive dyskinesia (TD) in older patients is known to be high, yet the course of TD in older patients has not been systematically studied. We followed 69 middle-aged and elderly outpatients newly diagnosed with TD in a naturalistic, longitudinal, prospective fashion. Standardized assessment instruments were administered to measure psychopathology, cognitive impairment, and abnormal movements. We observed a highly fluctuating early course of TD. Although the cumulative proportion of patients whose TD partially remitted was quite high (56% at 3 months, and 80% at 6 months), the cumulative proportion of patients whose TD relapsed (post-remission) was also high (33% at 3 months and 54% at 6 months). These findings may have clinical as well as theoretical implications for TD in older subjects.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0048-5764
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
187-91
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7831454-Aged,
pubmed-meshheading:7831454-Antipsychotic Agents,
pubmed-meshheading:7831454-Dyskinesia, Drug-Induced,
pubmed-meshheading:7831454-Female,
pubmed-meshheading:7831454-Humans,
pubmed-meshheading:7831454-Male,
pubmed-meshheading:7831454-Middle Aged,
pubmed-meshheading:7831454-Prospective Studies,
pubmed-meshheading:7831454-Schizophrenia
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pubmed:year |
1994
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pubmed:articleTitle |
Early course of new-onset tardive dyskinesia in older patients.
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pubmed:affiliation |
San Diego Veterans Affairs Medical Center, CA 92161.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|