Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-10-20
pubmed:abstractText
The rate of rRNA synthesis from E. coli DNA in vitro can exhibit an unusual temperature dependence. Instead of the typical sigmoid curve, at least five to six pronounced peaks of rRNA synthesis are detectable over a 30degrees range in temperature. rRNA synthesis from performed initiation complexes exhibits a similar pattern and shows that the number of polymerases able to initiate rRNA synthesis increases with each successive peak. These results are interpreted in terms of a model which proposes that the rRNA cistrons are served by multiple promoter sites (subpromoters) whose activation energies form a graded series. Thus the number of polymerases initiating rRNA synthesis could be controlled by regulating the number of active subpromoters.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
605-9
pubmed:dateRevised
2002-11-1
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Multiple modes of ribosomal RNA transcription in vitro.
pubmed:publicationType
Journal Article