| pubmed-article:7827114 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7827114 | lifeskim:mentions | umls-concept:C0327518 | lld:lifeskim |
| pubmed-article:7827114 | lifeskim:mentions | umls-concept:C0042479 | lld:lifeskim |
| pubmed-article:7827114 | lifeskim:mentions | umls-concept:C0025543 | lld:lifeskim |
| pubmed-article:7827114 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:7827114 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:7827114 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7827114 | pubmed:dateCreated | 1995-2-23 | lld:pubmed |
| pubmed-article:7827114 | pubmed:abstractText | A non-hemorrhagic metalloprotease (protease L4) was purified from the venom of Chinese Mamushi (Agkistrodon halys brevicaudus) by gel filtration and anion-exchange chromatography. Protease L4 has the molecular weight of 22,000 and its optimum pH was 8.5. The protein was stable in the pH range of 5-9 and below 40 degrees C. The proteolytic activity was inhibited by metal-chelating agents and some metal ions. Calcium ion activated the activity dose-dependently, but had only a minor effect on the thermal and pH stability. L4 showed fibrinogenase activity, hydrolyzing only the A alpha chain of fibrinogen. The protease cleaved preferentially at the N-terminal of Leu and His residues of some peptides. | lld:pubmed |
| pubmed-article:7827114 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7827114 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7827114 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7827114 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:7827114 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:FujimuraSS | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:KimotoEE | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:BabaSS | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:RikimaruTT | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:TeradaSS | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:HoriJJ | lld:pubmed |
| pubmed-article:7827114 | pubmed:author | pubmed-author:HaiX WXW | lld:pubmed |
| pubmed-article:7827114 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7827114 | pubmed:day | 18 | lld:pubmed |
| pubmed-article:7827114 | pubmed:volume | 1243 | lld:pubmed |
| pubmed-article:7827114 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7827114 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7827114 | pubmed:pagination | 94-100 | lld:pubmed |
| pubmed-article:7827114 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:meshHeading | pubmed-meshheading:7827114-... | lld:pubmed |
| pubmed-article:7827114 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7827114 | pubmed:articleTitle | Purification and characterization of a non-hemorrhagic metalloprotease from Agkistrodon halys brevicaudus venom. | lld:pubmed |
| pubmed-article:7827114 | pubmed:affiliation | Department of Chemistry, Faculty of Science, Fukuoka University, Japan. | lld:pubmed |
| pubmed-article:7827114 | pubmed:publicationType | Journal Article | lld:pubmed |
