Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1995-2-16
pubmed:abstractText
The protein encoded by katF (also known as nur, appR, csi-2, abrD, and rpoS in various alleles) has been biochemically confirmed to be an alternate sigma transcription factor and renamed sigma S. Its synthesis is controlled transcriptionally and posttranscriptionally by as yet undefined mechanisms that are active well into stationary phase. sigma S controls a regulon of 30 or more genes expressed in response to starvation and during the transition to stationary phase. Proteins in the regulon, many of which have not been characterized, enhance long-term survival in nutrient-deficient medium and have a diverse group of functions including protection against DNA damage, the determination of morphological changes, the mediation of virulence, osmoprotection, and thermotolerance. Differential expression of subfamilies of genes within the regulon is effected by supplementary regulatory factors, working both individually and in combination to modulate activity of different sigma S-dependent promoters.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0066-4227
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:geneSymbol
katF
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-80
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The role of the sigma factor sigma S (KatF) in bacterial global regulation.
pubmed:affiliation
Department of Microbiology, University of Manitoba, Winnipeg, Canada.
pubmed:publicationType
Journal Article, Review