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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-2-14
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pubmed:abstractText |
We sought to evaluate the effect of vertical transmission of human immunodeficiency virus type 1 (HIV-1) on birthweight and length of gestation. For this purpose we used maternal and pregnancy data of 559 HIV-1-seropositive pregnant women delivered at 13 Italian centers from 1985 to 1991. The mother-to-child transmission rate of HIV infection was 18.2% (84/461). After adjustment for potential confounders with multiple linear regression analysis, there were no differences in birthweight, gestational age, and proportion of expected birthweight (observed birthweight/expected birthweight) between infected and uninfected children. Intravenous drug abuse during current pregnancy was the factor which correlated best with a reduction in birthweight (mean reduction, 214.4 g; 95% confidence interval (CI), 61.7-367.1), length of gestation (mean reduction, 9.3 days; 95% CI, 3.9-14.7) and proportion of expected birthweight (mean reduction, 12.1%; 95% CI, 4.7-19.5%). In our population, HIV-1 infection of the fetus has little effect on length of gestation and birthweight.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0301-2115
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7821496-Adult,
pubmed-meshheading:7821496-Birth Weight,
pubmed-meshheading:7821496-Female,
pubmed-meshheading:7821496-Gestational Age,
pubmed-meshheading:7821496-HIV Infections,
pubmed-meshheading:7821496-HIV-1,
pubmed-meshheading:7821496-Humans,
pubmed-meshheading:7821496-Infant, Newborn,
pubmed-meshheading:7821496-Infectious Disease Transmission, Vertical,
pubmed-meshheading:7821496-Male,
pubmed-meshheading:7821496-Pregnancy,
pubmed-meshheading:7821496-Pregnancy Complications, Infectious,
pubmed-meshheading:7821496-Retrospective Studies,
pubmed-meshheading:7821496-Substance Abuse, Intravenous
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pubmed:year |
1994
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pubmed:articleTitle |
The effect of fetal infection with human immunodeficiency virus type 1 on birthweight and length of gestation. SIGO Study Group of HIV Infection in Pregnancy.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Pavia, IRCCS Policlinico S. Matteo, Italy.
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pubmed:publicationType |
Journal Article
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