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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1995-2-10
pubmed:abstractText
ST elevation is the basis of management decisions in acute myocardial infarction and may provide a quick means of stratifying patients. This is particularly relevant with inferior infarction because of the generally smaller benefit-to-risk ratio of reperfusion therapy. We studied the relationship between ST changes and the perfusion territory of the infarct-related artery in 95 patients: 77 with proximal right coronary related infarction (perfusion territory quantitated by an angiographic score maximum possible value = 1.0) and 18 with circumflex related infarction (divided angiographically into proximal and distal arterial occlusions). For right coronary related infarction, the angiographic score ranged widely from 0.25 to 0.82 (mean 0.53, standard deviation 0.13). Parameters that correlated with the angiographic score on univariate analysis were precordial ST depression (r = -0.59), inferior ST elevation (r = 0.51), and number of leads with ST change (r = 0.56). On multivariate analysis, only precordial ST depression and the number of leads with ST elevation were independent predictors of the angiographic score (r = 0.64), with precordial ST depression predicting the major portion of its variability. For circumflex related infarction, precordial ST depression was the only predictor of a proximal occlusion. Summed precordial ST depression > or = 0.3 mV, as compared to less or no ST depression, predicted a larger territory of the infarct-related artery (either a right coronary angiographic score >0.5 or a proximal left circumflex lesion, kappa = 0.51, P < 0.001). In acute inferior infarction, deep precordial ST depression reflects large jeopardized territory, a subgroup that may benefit more from aggressive reperfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0195-668X
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1385-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Implications of ST changes in reperfusion management of acute inferior myocardial infarction.
pubmed:affiliation
Hallstrom Institute of Cardiology, University of Sydney, Royal Prince Alfred Hospital, Australia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't