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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1995-2-10
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pubmed:abstractText |
One hundred and two patients participated in a 4 week programme of intensive exercise training early after myocardial infarction. Lipid levels were measured before and after exercise training. The mean exercise capacity increased by 49% (P = 0.0001). Twenty-one patients who continued smoking and 25 non-beta-blocked patients were considered to have an increased risk of recurrent cardiac events, as were patients with high initial lipid levels. In the smokers and non-beta-blocked patients total cholesterol decreased by 0.30 mmol.l-1 (P = 0.031) and 0.37 mmol.l-1 (P = 0.042) respectively and triglycerides by 0.28 mmol.l-1 (P = 0.058) and 0.13 mmol.l-1 (P = 0.11). Patients with high initial cholesterol and triglyceride levels had the largest cholesterol and triglyceride decrease, r = 0.43 (P = 0.0001) and r = 0.38 (P = 0.001) respectively. After adjusting for initial lipid levels, cholesterol (P = 0.036) as well as triglycerides (P = 0.034) decreased in patients without beta-blocker treatment whereas smoking no longer had an independent effect on lipid level decrease. HDL-cholesterol did not change in any group. Thus, after 4 weeks of exercise training lipid profiles were improved in patients with an increased risk of recurrent cardiac events. Beta-blocker treatment, however, seemed to hinder the beneficial effects of exercise training on lipid levels.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0195-668X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1362-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7821313-Adrenergic beta-Antagonists,
pubmed-meshheading:7821313-Cholesterol,
pubmed-meshheading:7821313-Cholesterol, HDL,
pubmed-meshheading:7821313-Exercise Therapy,
pubmed-meshheading:7821313-Exercise Tolerance,
pubmed-meshheading:7821313-Female,
pubmed-meshheading:7821313-Humans,
pubmed-meshheading:7821313-Lipids,
pubmed-meshheading:7821313-Male,
pubmed-meshheading:7821313-Middle Aged,
pubmed-meshheading:7821313-Myocardial Infarction,
pubmed-meshheading:7821313-Recurrence,
pubmed-meshheading:7821313-Risk Factors,
pubmed-meshheading:7821313-Smoking,
pubmed-meshheading:7821313-Time Factors,
pubmed-meshheading:7821313-Triglycerides
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pubmed:year |
1994
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pubmed:articleTitle |
Effects of intensive exercise training on lipid levels in high risk post-MI patients.
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pubmed:affiliation |
Department of Medicine, Aker University Hospital, Oslo, Norway.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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