Linked Life Data

7820206

Source:http://linkedlifedata.com/resource/pubmed/id/7820206

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-2-16
pubmed:abstractText
Nitric oxide is a gaseous endogenous mediator of vascular dilation, neural transmission, defense against microorganisms, and inhibitor of platelet adhesion. Endothelium-derived nitric oxide is important in the maintenance of normal vascular tone in the systemic and pulmonary circulation. The discovery of a selective pulmonary vasodilator has eluded investigators for many years. Inhaled nitric oxide can be used to selectively manipulate the pulmonary vasculature and represents an important advance in pharmacologic strategies aimed at the treatment of the diseased pulmonary circulation. Indeed, preliminary studies of the therapeutic use of inhaled nitric oxide in human pulmonary hypertension and respiratory failure are yielding encouraging and exciting results. Controlled and randomized studies will be required to show improvement in patient outcome and the absence of adverse sequelae from inhaled nitric oxide therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1040-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-90
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Therapeutic use of inhaled nitric oxide.
pubmed:affiliation
Cardiac ICU Office, Children's Hospital, Boston, MA 02115.
pubmed:publicationType
Journal Article, Review