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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1995-2-7
|
| pubmed:abstractText |
The effect of aging on muscle contractile function was examined in the anterior latissimus dorsi (ALD) muscle of Japanese quails aged 8 weeks (young adults), 26 weeks, 60 weeks, or 90 weeks (old birds). In vitro contractile measures of the ALD were made at 25 degrees C (stimulus pulse = 0.1 ms). Twitch contraction time in 90-week-old muscles was significantly greater than 8 to 26-week-old muscles (150 +/- 8 ms vs 168 +/- 18 ms). Similarly, one-half relaxation time of the twitch was increased in the ALD from old birds (221 +/- 17 ms) relative to adult birds 8-26 weeks (173 +/- 11). Aging produced a greater fusing of twitches at stimulation frequencies of 5 and 10 Hz, and this resulted in a leftward shift of the force-frequency curve at these frequencies. Shortening velocity measured by the force-velocity method (Vmax) decreased from 2.6 +/- 0.2 muscle length/s (mL/s) to 1.19 +/- 0.02 mL/s in 8 and 90-week-old muscles, respectively. Maximal velocity of unloaded shortening as measured by the slack test decreased from 3.6 +/- 0.7 mL/s to 2.4 mL/s in 8-week-old and 90-week-old muscles, respectively. Maximal tetanic force (60.6 +/- 3.1 mN) and specific force (11.3 +/- 0.3 N/cm2) were similar in young adult and old muscles. These data indicate that aging induces a slowing of both twitch contractile characteristics and shortening velocity in the ALD, without affecting maximal force capabilities.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1079-5006
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50A
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
B26-33
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
1995
|
| pubmed:articleTitle |
Slowing of contractile properties in quail skeletal muscle with aging.
|
| pubmed:affiliation |
Department of Exercise Science, Ohio State University.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
|