Linked Life Data

7814689

Source:http://linkedlifedata.com/resource/pubmed/id/7814689

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-2-8
pubmed:abstractText
In order to establish the specificity of growth and termination of dorsal root afferents within the developing spinal cord, the central dorsal horn terminals of myelinated sensory afferents were labelled at various stages in the rat from embryonic day (E)18 through to postnatal day (P) 35 using horseradish peroxidase conjugated to choleragenoid (B-HRP). The preferential labelling of A fibre afferents with this tracer was found to be as clear in the neonate as has been reported for the adult. The results show that while the somatotopic arrangement of A fibre afferent terminals in the dorsal horn is established early in development, the laminar projections are not. Following peripheral nerve or local skin injections of B-HRP, A fibre terminals were found to project throughout laminae I to V, including lamina II (substantia gelatinosa). This widespread termination was observed consistently until the end of the third postnatal week. After P22 the terminal field becomes restricted to the normal laminae III to V.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
348
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Developmental changes in the laminar termination of A fibre cutaneous sensory afferents in the rat spinal cord dorsal horn.
pubmed:affiliation
Department of Anatomy and Developmental Biology, University College London, United Kingdom.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't