Linked Life Data

7814422

Source:http://linkedlifedata.com/resource/pubmed/id/7814422

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-2-3
pubmed:abstractText
Select hydrogen-carbon distances have been determined from 13C[1H] heteronuclear Overhauser effects observed in a 99% carbon-13 enriched 13CO2H bilirubin analog, [8(3), 12(3)-13C2]-mesobilirubin XIII alpha. Analysis of the data confirms that the propionic acid carbonyl lies within hydrogen bonding distance to the dipyrrinone lactam and pyrrole N-H groups in chloroform and indicates, surprisingly, that those distances are only slightly longer in dimethyl sulfoxide solvent or when the carboxyl group is ionized in pH 7.4 aqueous buffered solutions of the pigment. The data supports the presence and persistence of folded, intramolecularly hydrogen-bonded bilirubin conformations in solution.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
270
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
On the structure of bilirubin in solution. 13C[1H] heteronuclear Overhauser effect NMR analyses in aqueous buffer and organic solvents.
pubmed:affiliation
Department of Chemistry, University of Nevada, Reno 89557-0020.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.