Linked Life Data

7813595

Source:http://linkedlifedata.com/resource/pubmed/id/7813595

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-2-8
pubmed:abstractText
Polyamines regulate cell division in developing brain. Neuronal membranes and the NMDA receptor have polyamine binding or functional sites. We have visualized [3H]spermidine binding in human cerebellum sections. Autoradiographs showed high specific [3H]spermidine binding in granule cell layer and low binding in molecular layer in neonate, infant and adult cerebellum which qualitatively resembled NMDA binding. Cerebellum from neonates and infants below 6 months had a further zone of dense [3H]spermidine binding in the external granule layer of migratory cells. This second zone may show a polyamine regulatory site for cerebellar development from fetal life to early infancy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
262
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
293-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
A polyamine binding site labelled with [3H]spermidine in developing human cerebellum.
pubmed:affiliation
School of Biological Sciences, Manchester University, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't