Linked Life Data

7812414

Source:http://linkedlifedata.com/resource/pubmed/id/7812414

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1995-2-7
pubmed:abstractText
The aim of this study was to assess evidence that genetic factors influence body fat distribution. First-degree relatives of 324 cancer-free females in a population-based prospective study of 41,837 women (99% white) between the ages of 55 and 69 at baseline in 1986 were studied. A total of 396 living sisters (mean age 65.7 years) and 446 living daughters (mean age 41.2 years) were identified through a mailed 'family tree' questionnaire sent to each participant. Family members were mailed a questionnaire to obtain self-reported measures of current height and weight. A paper tape measure and written instructions were enclosed to obtain waist and hip circumferences. The age-adjusted mother-daughters correlations for waist-to-hip ratio and body mass index (kg/m2) were 0.19 and 0.23, respectively (P < 0.05 using Fisher's z-transformation). The corresponding sister-sister correlations were 0.23 and 0.19, respectively (P < 0.05). The sister-sister correlations were not significantly different from the mother-daughter correlations. After adjustment for body mass index the mother-daughter correlation for waist-to-hip ratio increased to 0.20 and the sister-sister correlation increased to 0.26. These familial correlations suggest that genes and common environment may contribute 40 to 50% of the total variance of waist-to-hip ratio in white women in the Midwest.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0307-0565
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
607-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Familial aggregation and heritability of waist-to-hip ratio in adult women: the Iowa Women's Health Study.
pubmed:affiliation
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.