Linked Life Data

7809085

Source:http://linkedlifedata.com/resource/pubmed/id/7809085

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:7809085rdf:typepubmed:Citationlld:pubmed
pubmed-article:7809085lifeskim:mentionsumls-concept:C0006675lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0330390lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0332307lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0034721lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0027882lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0019564lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0521390lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C1171362lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0597712lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0040691lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C1545588lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0019868lld:lifeskim
pubmed-article:7809085lifeskim:mentionsumls-concept:C0851285lld:lifeskim
pubmed-article:7809085pubmed:issue26lld:pubmed
pubmed-article:7809085pubmed:dateCreated1995-2-2lld:pubmed
pubmed-article:7809085pubmed:abstractTextExcessive activation of glutamate receptors accompanied by Ca2+ overloading is thought to be responsible for the death of neurons in various conditions including stroke and epilepsy. Neurons also die if deprived of important growth factors and trophic influences, conditions sensitive to certain oncogene products such as the Bcl2 protein. We now demonstrate that transforming growth factor type beta (TGF-beta) prevents neuronal Ca2+ overloading of rat hippocampal neurons in response to the glutamatergic agonist N-methyl-D-aspartate or the Ca2+ ionophore 4-Br-A23187 and, in addition, leads to a substantial increase in neuronal Bcl2 protein expression. Parallel cytotoxicity experiments demonstrate that treatment with TGF-beta protects rat hippocampal neurons from death induced by excitotoxicity, trophic factor removal, and oxidative injury. Thus, TGF-beta may protect against a wide range of toxic insults by regulating two factors with great importance for neuronal viability.lld:pubmed
pubmed-article:7809085pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:languageenglld:pubmed
pubmed-article:7809085pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:citationSubsetIMlld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:7809085pubmed:statusMEDLINElld:pubmed
pubmed-article:7809085pubmed:monthDeclld:pubmed
pubmed-article:7809085pubmed:issn0027-8424lld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:ReedJ CJClld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:MillerR JRJlld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:KrajewskiSSlld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:PrehnJ HJHlld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:BindokasV PVPlld:pubmed
pubmed-article:7809085pubmed:authorpubmed-author:MarcuccilliC...lld:pubmed
pubmed-article:7809085pubmed:issnTypePrintlld:pubmed
pubmed-article:7809085pubmed:day20lld:pubmed
pubmed-article:7809085pubmed:volume91lld:pubmed
pubmed-article:7809085pubmed:ownerNLMlld:pubmed
pubmed-article:7809085pubmed:authorsCompleteYlld:pubmed
pubmed-article:7809085pubmed:pagination12599-603lld:pubmed
pubmed-article:7809085pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:meshHeadingpubmed-meshheading:7809085-...lld:pubmed
pubmed-article:7809085pubmed:year1994lld:pubmed
pubmed-article:7809085pubmed:articleTitleRegulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type beta confers wide-ranging protection on rat hippocampal neurons.lld:pubmed
pubmed-article:7809085pubmed:affiliationDepartment of Pharmacological and Physiological Sciences, University of Chicago, IL 60637.lld:pubmed
pubmed-article:7809085pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:7809085pubmed:publicationTypeIn Vitrolld:pubmed
pubmed-article:7809085pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:7809085pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:7809085lld:pubmed
More...