Linked Life Data

7805285

Source:http://linkedlifedata.com/resource/pubmed/id/7805285

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1995-1-31
pubmed:abstractText
Tissue plasminogen activator (tPA) expression during embryogenesis was determined by in situ hybridization of whole mouse embryos from E10.5 through E17.5. The strongest expression occurs in the basal midbrain and hindbrain, and continues posteriorly into the neural canal. This expression coincides with extensive cell migration and proliferation, and tissue remodelling of this region. tPA mRNA is also associated with cells that appear to be invading the cerebellar anlage. Presumptive proliferating and migrating cells in the olfactory neuroepithelium also express tPA. These results indicate that tPA is expressed by a number of different cell types in the developing nervous system and suggest a role for tPA in cell migration and tissue remodelling of the developing CNS.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0165-3806
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Tissue plasminogen activator expression in the embryonic nervous system.
pubmed:affiliation
Neuroscience Program, University of Colorado Health Sciences Center, Denver 80262.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.