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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1995-1-27
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pubmed:abstractText |
Somatostatin receptor scintigraphy with 111In-labeled octreotide proves to be a very sensitive diagnostic tool for evaluation of inflammative activity in endocrine ophthalmopathy (EO). The results of somatostatin receptor scintigraphy (SRS) in 40 patients with EO show a high orbital accumulation of 111In-octreotide in clinically active EO (4 h-median/orbit-brain-ratio: 12.6; controls 4 h-median: 5.8) Patients with clinically inactive EO (4 h-median: 7.1) show a similar orbital accumulation of radioactivity compared to controls. 5 patients with active orbital myositis also revealed an even higher orbital accumulation of radioactivity (4 h-median: 42.3). The diagnostic value of SRS lies in its ability to act as a measure of inflammation and can be useful as an activity parameter when planning therapeutic procedure as well as for EO follow-up. The results in patients with orbital myositis nevertheless do not permit a differential diagnosis with this method. The therapeutic value of 111In-octreotide in Graves' disease has yet to be established.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1438-9029
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
484-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7803769-Adult,
pubmed-meshheading:7803769-Aged,
pubmed-meshheading:7803769-Diagnosis, Differential,
pubmed-meshheading:7803769-Female,
pubmed-meshheading:7803769-Graves Disease,
pubmed-meshheading:7803769-Humans,
pubmed-meshheading:7803769-Indium Radioisotopes,
pubmed-meshheading:7803769-Male,
pubmed-meshheading:7803769-Middle Aged,
pubmed-meshheading:7803769-Octreotide,
pubmed-meshheading:7803769-Orbital Pseudotumor,
pubmed-meshheading:7803769-Receptors, Somatostatin
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pubmed:year |
1994
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pubmed:articleTitle |
[Somatostatin receptor scintigraphy in endocrine orbitopathy].
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pubmed:affiliation |
Klinik und Poliklinik für Nuklearmedizin, Johannes-Gutenberg-Universität Mainz.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Controlled Clinical Trial
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