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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1995-1-26
|
| pubmed:abstractText |
Several reports have shown that weak, extremely-low-frequency (ELF), pulsed magnetic fields (PMFs) can adversely affect the early embryonic development of the chick. In this study, freshly fertilized chicken eggs were exposed during the first 48 h of postlaying incubation to PMFs with 100 Hz repetition rate, 1.0 microT peak-to-peak amplitude, and 500 microseconds pulse duration. Two different pulse waveforms were used, having rise and fall times of 85 microseconds (PMF-A) or 2.1 microseconds (PMF-B). It has been reported that, with 2 day exposure, these fields significantly increase the proportion of developmental abnormalities. In the present study, following exposure, the eggs were allowed to incubate for an additional 9 days in the absence of the PMFs. The embryos were taken out of the eggs and studied blind. Each of the two PMF-exposed groups showed an excess in the percentage of developmental anomalies compared with the respective sham-exposed samples. This excess of anomalies was not significant for the PMF-A-treated embryos (P = 0.173), whereas it was significant for the PMF-B-exposed group (P = 0.007), which showed a particularly high rate of early embryonic death. These results reveal that PMFs can induce irreversible developmental alterations and confirm that the pulse waveform can be a determinant factor in the embryonic response to ELF magnetic fields. The data also validate previous work based on the study of PMFs' effects at day 2 of embryonic development under field exposure.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0197-8462
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
385-98
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:7802707-Abnormalities, Radiation-Induced,
pubmed-meshheading:7802707-Animals,
pubmed-meshheading:7802707-Bone and Bones,
pubmed-meshheading:7802707-Chick Embryo,
pubmed-meshheading:7802707-Congenital Abnormalities,
pubmed-meshheading:7802707-Death,
pubmed-meshheading:7802707-Electromagnetic Fields,
pubmed-meshheading:7802707-Hot Temperature,
pubmed-meshheading:7802707-Magnetics,
pubmed-meshheading:7802707-Reproducibility of Results,
pubmed-meshheading:7802707-Single-Blind Method,
pubmed-meshheading:7802707-Time Factors
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Chick embryo development can be irreversibly altered by early exposure to weak extremely-low-frequency magnetic fields.
|
| pubmed:affiliation |
Departamento de Investigación, Hospital Ramón y Cajal, Madrid, Spain.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|