Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-7-31
|
pubmed:abstractText |
In order to reduce corneal complications in 27 glaucomatous eyes that underwent trabeculectomy and postoperative subconjunctival injection of 5-fluorouracil we tried 1) a low-dose administration of 5-fluorouracil and 2) a modified subconjunctival injection technique. The mean total 5-fluorouracil dose was 18.0 +/- 6 mg. A life-table analysis showed a success rate, at 15 months, of 78% (+/- 7 S.E.). Four of the 27 eyes (13%) had corneal complications, limited to punctate keratopathy, with no corneal epithelial defects and/or abrasions. Our study shows that corneal complications decreased when the contact between 5-fluorouracil and the ocular surface was reduced.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0165-5701
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
247-50
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7797391-Adolescent,
pubmed-meshheading:7797391-Adult,
pubmed-meshheading:7797391-Aged,
pubmed-meshheading:7797391-Child,
pubmed-meshheading:7797391-Conjunctiva,
pubmed-meshheading:7797391-Corneal Diseases,
pubmed-meshheading:7797391-Fibrosis,
pubmed-meshheading:7797391-Fluorouracil,
pubmed-meshheading:7797391-Glaucoma,
pubmed-meshheading:7797391-Humans,
pubmed-meshheading:7797391-Injections,
pubmed-meshheading:7797391-Middle Aged,
pubmed-meshheading:7797391-Postoperative Complications,
pubmed-meshheading:7797391-Trabeculectomy
|
pubmed:articleTitle |
Decreased corneal complications after no-reflux, low-dose 5 fluorouracil subconjunctival injection following trabeculectomy.
|
pubmed:affiliation |
University Eye Clinic, Genova, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|