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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-8-2
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pubmed:abstractText |
Fifteen patients with refractory chronic idiopathic thrombocytopenic purpura (ITP) were treated with dapsone (100 mg/d) for 1-31 months. The overall response rate to dapsone was 40%. Five patients responded in 1 month and one patient in 2 months. No pretreatment characteristics--sex, age, platelet count or duration of ITP--were correlated with response to dapsone. Treatment was well tolerated. The most frequent adverse effect was dose-related haemolytic anaemia. In our experience, dapsone provides an inexpensive and well-tolerated alternative for patients with ITP who had inadequate responses to conventional therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
473-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7794776-Adolescent,
pubmed-meshheading:7794776-Adult,
pubmed-meshheading:7794776-Aged,
pubmed-meshheading:7794776-Aged, 80 and over,
pubmed-meshheading:7794776-Chronic Disease,
pubmed-meshheading:7794776-Dapsone,
pubmed-meshheading:7794776-Female,
pubmed-meshheading:7794776-Humans,
pubmed-meshheading:7794776-Middle Aged,
pubmed-meshheading:7794776-Purpura, Thrombocytopenic, Idiopathic,
pubmed-meshheading:7794776-Recurrence,
pubmed-meshheading:7794776-Treatment Outcome
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pubmed:year |
1995
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pubmed:articleTitle |
Dapsone for refractory chronic idiopathic thrombocytopenic purpura.
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pubmed:affiliation |
Department of Haematology, Hospital General Universitario, Valencia, Spain.
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pubmed:publicationType |
Journal Article
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