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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1995-7-21
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pubmed:abstractText |
S(+)-Ketamine is judged to produce more potent anesthesia than either the racemate or the R(-) ketamine isomer because of differential activation of specific cerebral receptors. Other than central nervous system effects, the most important side effects of ketamine occur in the cardiovascular system. We examined the direct cardiac effects of the isomers and the racemate of ketamine in the isolated perfused guinea pig heart.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1426-37; discussion 25A
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7793656-Animals,
pubmed-meshheading:7793656-Blood Pressure,
pubmed-meshheading:7793656-Coronary Circulation,
pubmed-meshheading:7793656-Depression, Chemical,
pubmed-meshheading:7793656-Guinea Pigs,
pubmed-meshheading:7793656-Heart,
pubmed-meshheading:7793656-Heart Conduction System,
pubmed-meshheading:7793656-Heart Rate,
pubmed-meshheading:7793656-Ketamine,
pubmed-meshheading:7793656-Oxygen Consumption,
pubmed-meshheading:7793656-Perfusion,
pubmed-meshheading:7793656-Receptors, Opioid,
pubmed-meshheading:7793656-Stereoisomerism
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pubmed:year |
1995
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pubmed:articleTitle |
Ketamine has stereospecific effects in the isolated perfused guinea pig heart.
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pubmed:affiliation |
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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