Linked Life Data

779170

Source:http://linkedlifedata.com/resource/pubmed/id/779170

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1976-8-23
pubmed:abstractText
Treatment of BN recipients with soluble WAG/Rij histocompatibility antigens (HCA) did not produce prolongation of (WAG/Rij X BN) F1 heart allografts but resulted in specific sensitization of the recipients in most cases. Three different anti-WAG/Rij sera (ADS) were tested, either alone or complexed in equivalence to 0.5 mg of HCA. Depending on the serum used, ADS alone produced only a moderate prolongation of heart allograft survival or had no effect at all. Antigen-antibody complexes given i.v. on days 0, 2, 4, 6, and 8 induced a prolonged or indefinite cardiac graft survival (greater than 200 days), as well as accelerated graft rejection, depending on the source of the ADS used in immune complex formation. One month after heart transplantation, BN recipients, treated with antigen-antibody complexes, demonstrated normal graft-versus-host reactivity of peripheral blood lymphocytes, but rejected donor-type skin grafts in a slightly delayed fashion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
454-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Prolongation of heterotropic heart allograft survival in rats by use of antigen-antibody complexes.
pubmed:publicationType
Journal Article