| pubmed-article:778880 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:778880 | lifeskim:mentions | umls-concept:C0520817 | lld:lifeskim |
| pubmed-article:778880 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:778880 | lifeskim:mentions | umls-concept:C0030567 | lld:lifeskim |
| pubmed-article:778880 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:778880 | lifeskim:mentions | umls-concept:C0233401 | lld:lifeskim |
| pubmed-article:778880 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:778880 | pubmed:dateCreated | 1976-8-23 | lld:pubmed |
| pubmed-article:778880 | pubmed:abstractText | Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subjects were assessed at intervals, both physically and psychiatrically. Forty patients were followed up for the full six-month period. The severity of physical signs and affective symptoms was shown to be significantly related at several stages of the investigation. Initially, the patients showed a high psychiatric morbidity. During treatment, 22 patients developed a depressive disorder, 12 or which had a history of previous depressive episodes. By contrast, of the 11 patients who showed very few affective symptoms during follow-up, none had a history of depression. Of the 22 patients with a depressive disorder, only two were in the anticholinergic/amantadine group, compared with nine and 11 in the other groups. L-dopa was not an effective antidepressant agent. The probable relevance of the findings of the study to the management of patients with Parkinson's disease is outlined. | lld:pubmed |
| pubmed-article:778880 | pubmed:language | eng | lld:pubmed |
| pubmed-article:778880 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:778880 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:778880 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:778880 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:778880 | pubmed:issn | 0033-2917 | lld:pubmed |
| pubmed-article:778880 | pubmed:author | pubmed-author:MarsdenC DCD | lld:pubmed |
| pubmed-article:778880 | pubmed:author | pubmed-author:MindhamR HRH | lld:pubmed |
| pubmed-article:778880 | pubmed:author | pubmed-author:ParkesJ DJD | lld:pubmed |
| pubmed-article:778880 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:778880 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:778880 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:778880 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:778880 | pubmed:pagination | 23-33 | lld:pubmed |
| pubmed-article:778880 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:778880 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:778880 | pubmed:articleTitle | Psychiatric symptoms during l-dopa therapy for Parkinson's disease and their relationship to physical disability. | lld:pubmed |
| pubmed-article:778880 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:778880 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:778880 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
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