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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-7-20
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pubmed:abstractText |
To use a novel, sensitive study design to detect a potential oral contraceptive (OC) and dirithromycin drug interaction by assessing the pharmacokinetics of the ethinyl estradiol (E2) component of a common OC and the potential failure of OC effectiveness.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Combined,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Synthetic,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Ethinyl Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Macrolides,
http://linkedlifedata.com/resource/pubmed/chemical/Mestranol,
http://linkedlifedata.com/resource/pubmed/chemical/Norethindrone,
http://linkedlifedata.com/resource/pubmed/chemical/Norinyl,
http://linkedlifedata.com/resource/pubmed/chemical/dirithromycin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0029-7844
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
78-84
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pubmed:dateRevised |
2009-10-26
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pubmed:meshHeading |
pubmed-meshheading:7784027-Adolescent,
pubmed-meshheading:7784027-Adult,
pubmed-meshheading:7784027-Anti-Bacterial Agents,
pubmed-meshheading:7784027-Contraceptives, Oral, Combined,
pubmed-meshheading:7784027-Contraceptives, Oral, Synthetic,
pubmed-meshheading:7784027-Erythromycin,
pubmed-meshheading:7784027-Ethinyl Estradiol,
pubmed-meshheading:7784027-Female,
pubmed-meshheading:7784027-Humans,
pubmed-meshheading:7784027-Macrolides,
pubmed-meshheading:7784027-Mestranol,
pubmed-meshheading:7784027-Metabolic Clearance Rate,
pubmed-meshheading:7784027-Norethindrone,
pubmed-meshheading:7784027-Ovulation
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pubmed:year |
1995
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pubmed:articleTitle |
Dirithromycin increases ethinyl estradiol clearance without allowing ovulation.
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pubmed:affiliation |
Drug Product Evaluation Unit, University of Kentucky Medical Center, Lexington, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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