| pubmed-article:7783608 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0027740 | lld:lifeskim |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0027754 | lld:lifeskim |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0027752 | lld:lifeskim |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0205276 | lld:lifeskim |
| pubmed-article:7783608 | lifeskim:mentions | umls-concept:C0086272 | lld:lifeskim |
| pubmed-article:7783608 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7783608 | pubmed:dateCreated | 1995-7-20 | lld:pubmed |
| pubmed-article:7783608 | pubmed:abstractText | An experimental model for local administration of neuronotrophic substances at the site of peripheral nerve lesion is presented. The model consists of a subcutaneously located silicone reservoir and a connecting tube with its distal end fixed in the proximity of the severed and repaired nerve. The results of the preliminary tests of the model are presented. Sixty Sprague-Dawley rats were divided into two groups: control (saline-treated) (n = 30) and NGF-treated (n = 30). After axotomy of the sciatic nerve, an epineurial repair is performed. NGF or saline is injected daily into the subcutaneous reservoir during the first 3 weeks after axotomy and a single dose in the fourth week. The regenerated nerve observed in the NGF-treated group after four weeks of treatment presents a greater percentage of myelinated axons, thicker myeline sheaths, and more mature endoneurial layers. This experimental model provides a reliable and quantitative way to deliver neuronotrophic substances in site and at different administration rates. | lld:pubmed |
| pubmed-article:7783608 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7783608 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7783608 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7783608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7783608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7783608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7783608 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7783608 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7783608 | pubmed:issn | 0738-1085 | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:RodríguezJJ | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:FernándezJJ | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:RodrigoJJ | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:MartínezDD | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:BilbaoGG | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:SantosF XFX | lld:pubmed |
| pubmed-article:7783608 | pubmed:author | pubmed-author:MayoralEE | lld:pubmed |
| pubmed-article:7783608 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7783608 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:7783608 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7783608 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7783608 | pubmed:pagination | 71-6 | lld:pubmed |
| pubmed-article:7783608 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
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| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:meshHeading | pubmed-meshheading:7783608-... | lld:pubmed |
| pubmed-article:7783608 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7783608 | pubmed:articleTitle | Experimental model for local administration of nerve growth factor in microsurgical nerve reconnections. | lld:pubmed |
| pubmed-article:7783608 | pubmed:affiliation | Experimental Surgery Unit, Hospital Universitario del Aire, Madrid, Spain. | lld:pubmed |
| pubmed-article:7783608 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7783608 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
