Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8965
|
pubmed:dateCreated |
1995-7-17
|
pubmed:abstractText |
Neuron-specific enolase (NSE) is among the biochemical markers in cerebrospinal fluid reported to be useful in the differential diagnosis of Creutzfeldt-Jakob disease from other dementing illnesses. In a group of 58 patients with definite and probable Creutzfeldt-Jakob disease, NSE concentrations (median 94.0, interquartile range 256 ng/mL) were significantly higher (p < 0.001) than in 26 control patients (9.5, 15.5 ng/mL). At a cut-off of 35 ng/mL an optimum sensitivity of 80% with a specificity of 92% for the diagnosis of Creutzfeldt-Jakob disease by NSE in cerebrospinal fluid was obtained.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0140-6736
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
345
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1609-10
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7783539-Aged,
pubmed-meshheading:7783539-Brain,
pubmed-meshheading:7783539-Clinical Enzyme Tests,
pubmed-meshheading:7783539-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:7783539-Female,
pubmed-meshheading:7783539-Humans,
pubmed-meshheading:7783539-Magnetic Resonance Imaging,
pubmed-meshheading:7783539-Male,
pubmed-meshheading:7783539-Middle Aged,
pubmed-meshheading:7783539-Phosphopyruvate Hydratase,
pubmed-meshheading:7783539-Sensitivity and Specificity,
pubmed-meshheading:7783539-Tomography, X-Ray Computed
|
pubmed:year |
1995
|
pubmed:articleTitle |
Cerebrospinal fluid concentration of neuron-specific enolase in diagnosis of Creutzfeldt-Jakob disease.
|
pubmed:affiliation |
Neurologische Klinik, Georg-August-Universität Göttingen, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|