| pubmed-article:7778790 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7778790 | lifeskim:mentions | umls-concept:C1512977 | lld:lifeskim |
| pubmed-article:7778790 | lifeskim:mentions | umls-concept:C0023828 | lld:lifeskim |
| pubmed-article:7778790 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:7778790 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:7778790 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:7778790 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7778790 | pubmed:dateCreated | 1995-7-7 | lld:pubmed |
| pubmed-article:7778790 | pubmed:abstractText | The human immunodeficiency virus-1 transactivator protein (tat) was codelivered efficiently with a reporter gene under the control of a tat-responsive DNA element using different formulations of cationic liposomes. Expression of a tat-responsive reporter gene was induced by incubating cells with a mixture of purified recombinant tat protein, reporter DNA, and liposomes. Different cell lines were tested successfully as targets for the codelivery. Tat was shown to trans-activate the codelivered virus promoter specifically in the cells tested. Codelivery of tat with DNA is a useful model for studying the function of trans-acting factors and their cis-acting DNA elements. The currently available methods such as foot-printing only reveal the binding, but not the functional consequence of the binding, of the factor with the element. In addition, this system may prove useful as a model for high level and regulated transgene expression in target cells. | lld:pubmed |
| pubmed-article:7778790 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7778790 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7778790 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7778790 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:7778790 | pubmed:issn | 0003-2697 | lld:pubmed |
| pubmed-article:7778790 | pubmed:author | pubmed-author:GayRR | lld:pubmed |
| pubmed-article:7778790 | pubmed:author | pubmed-author:HuangLL | lld:pubmed |
| pubmed-article:7778790 | pubmed:author | pubmed-author:BarsoumJJ | lld:pubmed |
| pubmed-article:7778790 | pubmed:author | pubmed-author:FarhoodHH | lld:pubmed |
| pubmed-article:7778790 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7778790 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:7778790 | pubmed:volume | 225 | lld:pubmed |
| pubmed-article:7778790 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7778790 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7778790 | pubmed:pagination | 89-93 | lld:pubmed |
| pubmed-article:7778790 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:7778790 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7778790 | pubmed:articleTitle | Codelivery to mammalian cells of a transcriptional factor with cis-acting element using cationic liposomes. | lld:pubmed |
| pubmed-article:7778790 | pubmed:affiliation | Department of Pharmacology, University of Pittsburgh, School of Medicine, Pennsylvania 15261, USA. | lld:pubmed |
| pubmed-article:7778790 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7778790 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7778790 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7778790 | lld:pubmed |
