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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1995-7-7
|
| pubmed:abstractText |
To identify phenomena that might explain a higher mortality-to-incidence ratio for prostate cancer among smokers, 359 patients with newly diagnosed tumors at a community hospital were analyzed by tumor stage and grade, host age, obesity, smoking habits and survival. Among the 235 men with nonstage A tumors, stage D disease was independently related to host smoking (odds ratio 2.1, 95% confidence interval 1.3 to 4.3, p = 0.015), as well as to higher tumor grade, younger host age and lack of obesity. Stage D disease was present in 69% of 16 heavy smokers, 41% of 44 other smokers and 31% of nonsmokers. The 5-year tumor-specific mortality rate was greater among smokers than nonsmokers with stage D2 disease (88% versus 63%, p < 0.05) or with nonstage A disease (39% versus 17%, p < 0.001). These observations are compatible with earlier metastasis and more aggressive subsequent tumor advancement in smokers, and indicate that smoking habits may contribute to differences in prostate cancer prognosis between populations.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0022-5347
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
154
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
153-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:7776411-Age Factors,
pubmed-meshheading:7776411-Aged,
pubmed-meshheading:7776411-Aged, 80 and over,
pubmed-meshheading:7776411-California,
pubmed-meshheading:7776411-Cause of Death,
pubmed-meshheading:7776411-Humans,
pubmed-meshheading:7776411-Incidence,
pubmed-meshheading:7776411-Logistic Models,
pubmed-meshheading:7776411-Male,
pubmed-meshheading:7776411-Middle Aged,
pubmed-meshheading:7776411-Neoplasm Staging,
pubmed-meshheading:7776411-Obesity,
pubmed-meshheading:7776411-Odds Ratio,
pubmed-meshheading:7776411-Prognosis,
pubmed-meshheading:7776411-Prostatic Neoplasms,
pubmed-meshheading:7776411-Retrospective Studies,
pubmed-meshheading:7776411-Smoking,
pubmed-meshheading:7776411-Survival Rate
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
A worse prognosis for smokers with prostate cancer.
|
| pubmed:affiliation |
Department of Family Practice, University of California Medical School at Davis, Redding, USA.
|
| pubmed:publicationType |
Journal Article
|