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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1995-7-13
|
| pubmed:abstractText |
Many growth factors and cytokines promote receptor clustering on binding. At least three different protein-protein interaction sites are involved: cytokine-receptor I, cytokine-receptor II and receptor I-receptor II. Although structural data on these complexes are limited, recent structural and mutagenesis studies of the four-helix bundle class of cytokines are clarifying the nature of the complexes formed.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0959-440X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
114-21
|
| pubmed:dateRevised |
2009-9-29
|
| pubmed:meshHeading |
pubmed-meshheading:7773741-Animals,
pubmed-meshheading:7773741-Cytokines,
pubmed-meshheading:7773741-Growth Substances,
pubmed-meshheading:7773741-Humans,
pubmed-meshheading:7773741-Protein Conformation,
pubmed-meshheading:7773741-Receptors, Cytokine,
pubmed-meshheading:7773741-Receptors, Growth Factor
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Four-helix bundle growth factors and their receptors: protein-protein interactions.
|
| pubmed:affiliation |
University of Oxford, UK.
|
| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|