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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1995-7-11
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pubmed:abstractText |
Experiments on CBA mice established that acute intoxication with dimethylchlorovinyl phosphate given in a single LD50 of 1.0 increased mice splenic colony-forming cells, decreased thymic T cells, delayed hypersensitivity, natural and antibody-dependent cellular cytotoxicities, sheep splenic red blood cells, thymus-independent Vi antigen antibody production. The antidote therapy with atropine (20 mg/kg) did not stop the main manifestations of posttoxication immunodeficiency and enhanced the suppression of a humoral immune response to sheep red blood cells. Dipyroxim (15 mg/kg) diminished manifestations of postintoxication immunodeficiency.
|
pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0869-2092
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7773092-Acute Disease,
pubmed-meshheading:7773092-Animals,
pubmed-meshheading:7773092-Antibody Formation,
pubmed-meshheading:7773092-Antidotes,
pubmed-meshheading:7773092-Antigen-Antibody Reactions,
pubmed-meshheading:7773092-Atropine,
pubmed-meshheading:7773092-Dichlorvos,
pubmed-meshheading:7773092-Drug Evaluation, Preclinical,
pubmed-meshheading:7773092-Immunity, Cellular,
pubmed-meshheading:7773092-Mice,
pubmed-meshheading:7773092-Mice, Inbred CBA,
pubmed-meshheading:7773092-Poisoning,
pubmed-meshheading:7773092-Trimedoxime
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pubmed:articleTitle |
[The effect of antidote preparations on the immune reactions in acute dimethyl dichlorovinyl phosphate poisoning].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|