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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-7-7
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pubmed:abstractText |
Converging evidence suggests there is a specific role of dorso-lateral-prefrontal cortex (DLPC) in schizophrenic disorders and of orbito-frontal cortex (OFC) in obsessive-compulsive disorder (OCD). Here, 25 schizophrenic and 25 OCD patients were evaluated with Wisconsin Card Sorting Test and Object Alternation Test; neuropsychological tools sensitive to DLPC and OFC damage, respectively; and compared with 25 subjects of a control group. Moreover, they all underwent Weigl's Sorting Test and the Word Fluency Test to assess global frontal functioning. The results indicated a DLPC deficit in schizophrenia and an OFC involvement in OCD. These data suggest that functional disorders of the central nervous system can be explored with neuropsychological instruments.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0278-2626
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
202-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7772333-Adult,
pubmed-meshheading:7772333-Female,
pubmed-meshheading:7772333-Frontal Lobe,
pubmed-meshheading:7772333-Humans,
pubmed-meshheading:7772333-Male,
pubmed-meshheading:7772333-Neuropsychological Tests,
pubmed-meshheading:7772333-Obsessive-Compulsive Disorder,
pubmed-meshheading:7772333-Prefrontal Cortex,
pubmed-meshheading:7772333-Psychometrics,
pubmed-meshheading:7772333-Reference Values,
pubmed-meshheading:7772333-Schizophrenia,
pubmed-meshheading:7772333-Schizophrenic Psychology
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pubmed:year |
1995
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pubmed:articleTitle |
Frontal lobe dysfunction in schizophrenia and obsessive-compulsive disorder: a neuropsychological study.
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pubmed:affiliation |
Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study
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