| pubmed-article:7771795 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0682610 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0311400 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0102190 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:7771795 | lifeskim:mentions | umls-concept:C0032172 | lld:lifeskim |
| pubmed-article:7771795 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7771795 | pubmed:dateCreated | 1995-7-3 | lld:pubmed |
| pubmed-article:7771795 | pubmed:abstractText | The metabolism of platelet-activating factor (PAF) by isolated rat intestinal epithelial cells was investigated using 1-[3H]octadecyl-2-acetyl-sn-glycero-3-phosphocholine. The principal metabolite produced by the cells was 1-O-alkylglycerol, which was found in association with the cells and the medium. When similar studies were conducted employing an intestinal epithelial cell line (INT 407), PAF was almost quantitatively converted into 1-alkyl-2-acyl-sn-glycero-3-phosphocholine (AAGPC). When the intestinal epithelial cell microsomes were incubated in the presence of fluoride to inhibit phosphohydrolase activity, the formation of 1-alkylglycerol was decreased in association with a stoichiometric increase in 1-alkyl-glycerophosphate, indicating the presence of a lysophospholipase D in the intestinal cells. When the phospholipase D activity was examined in the microsomal fraction prepared from intestinal epithelial cells, lyso-PAF was the preferred substrate and only trace amounts of lyso-PAF were converted into alkylacyl-GPC. Acyllyso-GPC was rapidly cleaved to form free fatty acids. The absence of lysophospholipase D activity in INT 407 cells cannot be attributed to the absence of brush border in these cells since no lysophospholipase D activity was present in isolated brush border preparations. | lld:pubmed |
| pubmed-article:7771795 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7771795 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7771795 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7771795 | pubmed:month | May | lld:pubmed |
| pubmed-article:7771795 | pubmed:issn | 0003-9861 | lld:pubmed |
| pubmed-article:7771795 | pubmed:author | pubmed-author:JohnstonJ MJM | lld:pubmed |
| pubmed-article:7771795 | pubmed:author | pubmed-author:FurukawaMM | lld:pubmed |
| pubmed-article:7771795 | pubmed:author | pubmed-author:FrenkelR ARA | lld:pubmed |
| pubmed-article:7771795 | pubmed:author | pubmed-author:MugurumaKK | lld:pubmed |
| pubmed-article:7771795 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7771795 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:7771795 | pubmed:volume | 319 | lld:pubmed |
| pubmed-article:7771795 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7771795 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7771795 | pubmed:pagination | 274-80 | lld:pubmed |
| pubmed-article:7771795 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:7771795 | pubmed:meshHeading | pubmed-meshheading:7771795-... | lld:pubmed |
| pubmed-article:7771795 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7771795 | pubmed:articleTitle | Metabolic fate of platelet-activating factor in the rat enterocyte: the role of a specific lysophospholipase D. | lld:pubmed |
| pubmed-article:7771795 | pubmed:affiliation | Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas 75235-9051, USA. | lld:pubmed |
| pubmed-article:7771795 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7771795 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:7771795 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:7771795 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7771795 | lld:pubmed |
