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pubmed-article:7770717pubmed:abstractTextHistamine-2 receptor antagonist (H2-RA) have been shown to improve the function of various parts of the immune system. The proposed mechanism of the immunomodulative effects of H2-RA has been considered to be the inhibition of suppressor T-lymphocyte activity, an increase in interleukin-2 production, and an enhancement of natural killer cell activity. Most of these studies were done with cimetidine. Comparative data with other H2-RA are limited and conflict on immunomodulative effects. Comparison of the actions of H2-RA on the immune system is required.lld:pubmed
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pubmed-article:7770717pubmed:articleTitleComparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients.lld:pubmed
pubmed-article:7770717pubmed:affiliationDept. of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.lld:pubmed
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