rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1995-7-6
|
pubmed:abstractText |
Histamine-2 receptor antagonist (H2-RA) have been shown to improve the function of various parts of the immune system. The proposed mechanism of the immunomodulative effects of H2-RA has been considered to be the inhibition of suppressor T-lymphocyte activity, an increase in interleukin-2 production, and an enhancement of natural killer cell activity. Most of these studies were done with cimetidine. Comparative data with other H2-RA are limited and conflict on immunomodulative effects. Comparison of the actions of H2-RA on the immune system is required.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0036-5521
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
265-71
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7770717-Adjuvants, Immunologic,
pubmed-meshheading:7770717-Case-Control Studies,
pubmed-meshheading:7770717-Cimetidine,
pubmed-meshheading:7770717-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:7770717-Famotidine,
pubmed-meshheading:7770717-Female,
pubmed-meshheading:7770717-Humans,
pubmed-meshheading:7770717-Killer Cells, Natural,
pubmed-meshheading:7770717-Leukocytes, Mononuclear,
pubmed-meshheading:7770717-Lymphocyte Activation,
pubmed-meshheading:7770717-Male,
pubmed-meshheading:7770717-Middle Aged,
pubmed-meshheading:7770717-Ranitidine,
pubmed-meshheading:7770717-Receptors, Interleukin-2,
pubmed-meshheading:7770717-Stomach Neoplasms
|
pubmed:year |
1995
|
pubmed:articleTitle |
Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients.
|
pubmed:affiliation |
Dept. of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
|