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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1995-6-30
|
| pubmed:abstractText |
This study was designed to define the effects of beta-adrenergic blockade on aortic lysyl oxidase (LO), an enzyme responsible for elastin and collagen cross-linking, and aneurysm formation in the blotchy mouse. It was hypothesized that beta-blockade would inhibit the development of aneurysms because of its hemodynamic effect rather than a direct effect on LO activity.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0741-5214
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
21
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
792-9; discussion 799-800
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7769737-Animals,
pubmed-meshheading:7769737-Aorta, Thoracic,
pubmed-meshheading:7769737-Aortic Aneurysm,
pubmed-meshheading:7769737-Atenolol,
pubmed-meshheading:7769737-Blood Pressure,
pubmed-meshheading:7769737-Heart Rate,
pubmed-meshheading:7769737-Male,
pubmed-meshheading:7769737-Mice,
pubmed-meshheading:7769737-Mice, Mutant Strains,
pubmed-meshheading:7769737-Nadolol,
pubmed-meshheading:7769737-Propranolol,
pubmed-meshheading:7769737-Protein-Lysine 6-Oxidase
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Inhibition of aortic aneurysm development in blotchy mice by beta adrenergic blockade independent of altered lysyl oxidase activity.
|
| pubmed:affiliation |
Department of Surgery, University of Michigan School of Medicine, Ann Arbor, USA.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|