Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1995-6-30
pubmed:abstractText
The level of plasma endothelin-1 (ET-1) was measured with radioimmunoassay in 36 patients with chronic pulmonale before and after treatment. The results showed that ET-1 level was significantly higher in cor pulmonale patients (P < 0.001) and decreased significantly after treatment (P < 0.001), but was still higher than that in controls (P < 0.002). There was significant negative correlation between PaO2, pH and ET-1 level. A significant positive correlation was found between ET-1 level and PaCO2. The results suggest that ET-1 may play an important role in the pathophysiological process of chronic cor pulmonale and the drugs which can influence plasma ET-1 level may be used in the treatment of the disease.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0578-1426
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
821-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[A study on changes of plasma endothelin-1 level in patients with chronic cor pulmonale].
pubmed:affiliation
Department of Medicine, Affiliated Hospital of Qingdao Medical College.
pubmed:publicationType
Journal Article, English Abstract