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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1995-6-30
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pubmed:abstractText |
The level of plasma endothelin-1 (ET-1) was measured with radioimmunoassay in 36 patients with chronic pulmonale before and after treatment. The results showed that ET-1 level was significantly higher in cor pulmonale patients (P < 0.001) and decreased significantly after treatment (P < 0.001), but was still higher than that in controls (P < 0.002). There was significant negative correlation between PaO2, pH and ET-1 level. A significant positive correlation was found between ET-1 level and PaCO2. The results suggest that ET-1 may play an important role in the pathophysiological process of chronic cor pulmonale and the drugs which can influence plasma ET-1 level may be used in the treatment of the disease.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0578-1426
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
821-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7768140-Aged,
pubmed-meshheading:7768140-Blood Gas Analysis,
pubmed-meshheading:7768140-Chronic Disease,
pubmed-meshheading:7768140-Endothelins,
pubmed-meshheading:7768140-Female,
pubmed-meshheading:7768140-Humans,
pubmed-meshheading:7768140-Male,
pubmed-meshheading:7768140-Middle Aged,
pubmed-meshheading:7768140-Pulmonary Heart Disease,
pubmed-meshheading:7768140-Radioimmunoassay
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pubmed:year |
1994
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pubmed:articleTitle |
[A study on changes of plasma endothelin-1 level in patients with chronic cor pulmonale].
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pubmed:affiliation |
Department of Medicine, Affiliated Hospital of Qingdao Medical College.
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pubmed:publicationType |
Journal Article,
English Abstract
|