Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-7-5
pubmed:abstractText
The authors investigated a group of 195 patients from the Centre of Oncological Prevention for human papillomavirus (HPV) in the lower genital tract. The diagnostic set ViraPap/ViraType was used for detection. It is based on double hybridisation of viral DNA and on the use of polyclonal and monoclonal antibodies with chemoluminiscent reaction. The test was totally positive in 23.1% of women. 5.1% tests were positive in the low-risk group of viruses (LR-HPV) and 19.5% in the high risk group (HR-HPV). Precancerous lesions (CIN I-III) or invasive cancer were found in 86.7% of positive tests. In patients with CIN III 37.1% were HPV positive and all patients with invasive cancer were positive. The results support an association between CIN and HPV infections. The possible role of HPV in cancerogenesis is discussed as well as the clinical importance of their detection.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1210-7832
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Diagnosis of human papillomaviruses in the lower genital tract using the ViraPap/ViraType detection kit].
pubmed:affiliation
II. gynek.-porod. klinika 1. LF UK, Praha.
pubmed:publicationType
Journal Article, English Abstract