| pubmed-article:7761429 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7761429 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:7761429 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7761429 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
| pubmed-article:7761429 | lifeskim:mentions | umls-concept:C0023884 | lld:lifeskim |
| pubmed-article:7761429 | lifeskim:mentions | umls-concept:C0205197 | lld:lifeskim |
| pubmed-article:7761429 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:7761429 | pubmed:dateCreated | 1995-6-29 | lld:pubmed |
| pubmed-article:7761429 | pubmed:abstractText | We have developed a system for studying hepatocellular growth potential in which liver cells are introduced into the diseased livers of albumin-urokinase (Alb-uPA) transgenic mice. To use this system to study xenogeneic cell transplantation, rat liver cells were introduced into immunotolerant Alb-uPA transgenic mice. In regenerated recipient livers, up to 100% of hepatocellular gene expression was of rat origin, demonstrating the creation of a functional mouse liver in which parenchyma is derived from xenogeneic (rat) hepatocytes. Immunotolerant Alb-uPA transgenic mice provide a tool for studying hepatocellular biology of any species, including humans, in a controlled experimental setting. | lld:pubmed |
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| pubmed-article:7761429 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7761429 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7761429 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7761429 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7761429 | pubmed:month | May | lld:pubmed |
| pubmed-article:7761429 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:7761429 | pubmed:author | pubmed-author:BrinsterR LRL | lld:pubmed |
| pubmed-article:7761429 | pubmed:author | pubmed-author:PalmiterR DRD | lld:pubmed |
| pubmed-article:7761429 | pubmed:author | pubmed-author:SandgrenE PEP | lld:pubmed |
| pubmed-article:7761429 | pubmed:author | pubmed-author:RhimJ AJA | lld:pubmed |
| pubmed-article:7761429 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7761429 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:7761429 | pubmed:volume | 92 | lld:pubmed |
| pubmed-article:7761429 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7761429 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7761429 | pubmed:pagination | 4942-6 | lld:pubmed |
| pubmed-article:7761429 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:7761429 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7761429 | pubmed:articleTitle | Complete reconstitution of mouse liver with xenogeneic hepatocytes. | lld:pubmed |
| pubmed-article:7761429 | pubmed:affiliation | Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA. | lld:pubmed |
| pubmed-article:7761429 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7761429 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:7761429 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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