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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1995-6-29
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pubmed:abstractText |
Cerebrospinal fluid (CSF) from 20 infants who died of sudden infant death syndrome (SIDS), 7 cases of infectious death and 5 cases of violent death were examined with respect to concentrations of interleukin-6 (IL-6). The measurements were performed by ELISA. IL-6 levels in SIDS were significantly lower than in infectious death (p < 0.02), but significantly higher than in violent death (p < 0.02). Since IL-6 plays an important role in immune responses and may induce fever, the findings may suggest that immune activation plays a role in SIDS. The presence of cytokines in the central nervous system (CNS) may cause respiratory depression, especially in vulnerable infants.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7756807-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7756807-Female,
pubmed-meshheading:7756807-Humans,
pubmed-meshheading:7756807-Infant,
pubmed-meshheading:7756807-Infant, Newborn,
pubmed-meshheading:7756807-Infection,
pubmed-meshheading:7756807-Interleukin-6,
pubmed-meshheading:7756807-Male,
pubmed-meshheading:7756807-Postmortem Changes,
pubmed-meshheading:7756807-Sudden Infant Death,
pubmed-meshheading:7756807-Time Factors,
pubmed-meshheading:7756807-Violence
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pubmed:year |
1995
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pubmed:articleTitle |
SIDS cases have increased levels of interleukin-6 in cerebrospinal fluid.
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pubmed:affiliation |
Institute of Forensic Medicine, Rikshospitalet, Oslo, Norway.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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