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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1995-6-26
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pubmed:abstractText |
For many years, membrane potential (Vm) and input resistance have been used to characterize the electrophysiological nature of a seal (barrier) that forms at the cut end of a transected axon or other extended cytoplasmic structure. Data from a mathematical and an analog model of a transected axon and other theoretical considerations show that steady-state values of Vm and input resistance measured from any cable-like structure provide a very equivocal assessment of the electrical barrier (seal) at the cut end. Extracellular assessments of injury currents almost certainly provide a better electrophysiological measure of the status of plasma membrane sealing because measurements of these currents do not depend on the cable properties of extended cytoplasmic processes after transection.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-13000763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-2185846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-3130467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-3836011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-4009251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-4421919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-4515629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-5352228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-5503279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-6658457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-7455707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-7965066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7756546-8492108
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0006-3495
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
795-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1995
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pubmed:articleTitle |
Membrane potential and input resistance are ambiguous measures of sealing of transected cable-like structures.
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pubmed:affiliation |
Department of Physiology and Biophysics, University of Texas Medical Branch, Galveston 77555-0641, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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