Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-6-21
pubmed:databankReference
pubmed:abstractText
Two chicken ribosomal protein S6 cDNAs were isolated from a liver cDNA library and their DNA sequence determined. Each of the cDNAs was found to use a different polyadenylation signal and to be polyadenylated at a different site. This is the first observation of alternative Poly(A) site usage by a ribosmal protein gene. Northern blot analysis revealed that the chicken rpS6 transcripts can be alternatively polyadenylated in brain tissue. Southern blot analysis indicates that there is only one rpS6 gene in the chicken genome. The long open reading frame of the chicken rpS6 gene specifies 249 amino acids which show high homology with rpS6 homologues from other species. The four serine residues in rpS6 which are major sites of phosphorylation in mammals are conserved in chicken.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
210
pubmed:geneSymbol
rpS6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
384-91
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Use of alternative polyadenylation sites by the chicken S6 ribosomal protein gene.
pubmed:affiliation
Eukaryotic Gene Organization and Expression Laboratory, Imperial Cancer Research Fund, London, United Kingdom.
pubmed:publicationType
Journal Article