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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1995-6-21
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pubmed:abstractText |
Hematologic toxicity of an antineoplastic drug, carboplatin, is largely dependent on its pharmacokinetics. Its therapeutic efficacy may be related to plasma drug exposure. Dosage adjustment based on isotopic determination of glomerular filtration rate has been proposed, but its ambulatory use is not yet conceivable. The dosage adjustment based on a patient's creatinine clearance relies on accurate measurement of urine volume per unit time and can be done with ease.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0027-8874
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
573-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7752255-Adult,
pubmed-meshheading:7752255-Aged,
pubmed-meshheading:7752255-Carboplatin,
pubmed-meshheading:7752255-Female,
pubmed-meshheading:7752255-Glomerular Filtration Rate,
pubmed-meshheading:7752255-Humans,
pubmed-meshheading:7752255-Kidney,
pubmed-meshheading:7752255-Male,
pubmed-meshheading:7752255-Metabolic Clearance Rate,
pubmed-meshheading:7752255-Middle Aged,
pubmed-meshheading:7752255-Models, Biological,
pubmed-meshheading:7752255-Prospective Studies,
pubmed-meshheading:7752255-Regression Analysis
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pubmed:year |
1995
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pubmed:articleTitle |
Prediction of carboplatin clearance from standard morphological and biological patient characteristics.
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pubmed:affiliation |
Centre Claudius Regaud, Toulouse, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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