rdf:type |
|
lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0007590,
umls-concept:C0007634,
umls-concept:C0014834,
umls-concept:C0033684,
umls-concept:C0449432,
umls-concept:C0596988,
umls-concept:C0678594,
umls-concept:C1179435,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1704735,
umls-concept:C1705248
|
pubmed:issue |
10-11
|
pubmed:dateCreated |
1995-6-22
|
pubmed:abstractText |
Two alleles of ftsA, a gene that encodes an essential cell division protein in Escherichia coli, have-been mapped at the nucleotide level. The mutations are located inside domains that are conserved in an ATP-binding protein family. The ftsA2 mutation lies in the adenine-binding domain, and the ftsA3 in the ribose-binding domain. The defect in ampicillin binding to PBP3 described for allele ftsA3 is allele-specific. This supports the hypothesis of the existence of different domains in FtsA having different functions.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-9084
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
76
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1071-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7748929-Alleles,
pubmed-meshheading:7748929-Ampicillin,
pubmed-meshheading:7748929-Bacterial Proteins,
pubmed-meshheading:7748929-Cell Compartmentation,
pubmed-meshheading:7748929-Cell Division,
pubmed-meshheading:7748929-Chromosome Mapping,
pubmed-meshheading:7748929-Escherichia coli,
pubmed-meshheading:7748929-Escherichia coli Proteins,
pubmed-meshheading:7748929-Genes, Bacterial,
pubmed-meshheading:7748929-Genes, Regulator,
pubmed-meshheading:7748929-Mutation,
pubmed-meshheading:7748929-Radioligand Assay
|
pubmed:year |
1994
|
pubmed:articleTitle |
Characterisation of mutant alleles of the cell division protein FtsA, a regulator and structural component of the Escherichia coli septator.
|
pubmed:affiliation |
Departamento de Biología Celular y del Desarrollo, CIB, CSIC, Madrid, Spain.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|