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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1995-6-14
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pubmed:abstractText |
Twenty outpatients with locally advanced (inoperable) or metastatic transitional cell carcinomas of the bladder were treated with carboplatin (300 mg/m2 i.v., day 1) + methotrexate (40 mg/m2 days 1 and 8) + vinblastine (6 mg/m2 days 1 and 8) (CaMV), every 4 weeks. One patient died of disease progression before completing at least 2 cycles of chemotherapy. Seven patients (35%) obtained a partial response; 8 had disease stabilization (40%) and 4 progressed (20%). Median duration of response was 3 months (range: 3-9), and median overall survival was 12+ months (range: 1-18+). None of the patients suffered grade IV toxicities, and no nephro-, neuro-, or ototoxicity was observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0277-3732
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
223-5
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7747710-Aged,
pubmed-meshheading:7747710-Ambulatory Care,
pubmed-meshheading:7747710-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7747710-Carboplatin,
pubmed-meshheading:7747710-Carcinoma, Transitional Cell,
pubmed-meshheading:7747710-Female,
pubmed-meshheading:7747710-Humans,
pubmed-meshheading:7747710-Male,
pubmed-meshheading:7747710-Methotrexate,
pubmed-meshheading:7747710-Middle Aged,
pubmed-meshheading:7747710-Remission Induction,
pubmed-meshheading:7747710-Urinary Bladder Neoplasms,
pubmed-meshheading:7747710-Vinblastine
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pubmed:year |
1995
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pubmed:articleTitle |
Carboplatin, methotrexate, and vinblastine in outpatients with advanced transitional cell carcinoma of the bladder.
|
pubmed:affiliation |
Unità Operativa di Oncologia Medica, Ospedale S. Andrea, La Spezia, Italy.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase II
|